WebThe BBA Molecular and Cell Biology of Lipids section publishes papers on original research dealing with novel aspects of molecular genetics related to the lipidome, the biosynthesis of lipids, the role of lipids in cells and whole organisms, the regulation of lipid metabolism and function, and lipidomics in all organisms. Manuscripts should ... Web70 rows · BBA Molecular and Cell Biology of Lipids publishes papers on original research dealing with novel aspects of lipid biology including the biosynthesis, degradation, and transport of lipids, the role of lipids and …
Molecular simulations of glycolipids: Towards mammalian cell …
WebJun 1, 2024 · Lipidomics is a subfield of metabolic phenotyping that focuses on high-throughput profiling and quantification of lipids. Essential roles of lipidomics in translational and clinical research have emerged, especially over the past decade. Most lipidomic pipelines have been developed using mass spectrometry (MS)-based methods. Because … WebLipid droplets are cytoplasmic organelles that store neutral lipids and are critically important for energy metabolism. Their function in energy storage is firmly established and … set cobblestones
Direct Detection of Domains in Phospholipid Bilayers by Grazing ...
WebApr 12, 2024 · Among the phospholipase A2 (PLA2) family, the secreted PLA2 (sPLA2) family in mammals contains 11 members that exhibit unique tissue or cellular distributions and enzymatic properties. Current studies using knockout and/or transgenic mice for a nearly full set of sPLA2s, in combination with comprehensive lipidomics, have revealed … WebThe mitochondrial calcium uniporter is a highly selective calcium (Ca 2+) channel complex present in the inner mitochondrial membrane (IMM) and is distributed widely across eukaryotic life with lineage specific losses (1–3).In response to physiological cues, the uniporter enables mitochondria to take up large amounts of Ca 2+ from the cytoplasm, … WebAbstract. Lysosomal acid lipase (LAL) is the sole enzyme known to degrade neutral lipids in the lysosome. Mutations in the LAL-encoding LIPA gene lead to rare lysosomal lipid storage disorders with complete or partial absence of LAL activity. This review discusses the consequences of defective LAL-mediated lipid hydrolysis on cellular lipid ... set cobalt